Document Type

Article

Publication Date

1-28-2013

Publication Source

Molecular Vision

Abstract

Purpose: Notophthalmus viridescens, the red-spotted newt, possesses tremendous regenerative capabilities. Among the tissues and organs newts can regenerate, the lens is regenerated via transdifferentiation of the pigment epithelial cells of the dorsal iris, following complete removal (lentectomy). Under normal conditions, the same cells from the ventral iris are not capable of regenerating. This study aims to further understand the initial signals of lens regeneration.

Inclusive pages

135-145

ISBN/ISSN

1090-0535

Document Version

Published Version

Publisher

Molecular Vision

Volume

19

Peer Reviewed

yes

Keywords

Molecular Vision, Article, Oxidative Stress, Adult Newt, Tool, Dedifferentiation, Complex, Cells


Included in

Biology Commons

COinS