Document Type
Article
Publication Date
9-2002
Publication Source
Development
Abstract
Teashirt (tsh) encodes a Drosophila zinc-finger protein. Misexpression of tsh has been shown to induce ectopic eye formation in the antenna. We report that tsh can suppress eye development. This novel function of tsh is due to the induction of homothorax (hth), a known repressor of eye development, and requires Wingless (WG) signaling. Interestingly, tsh has different functions in the dorsal and ventral eye, suppressing eye development close to the ventral margin, while promoting eye development near the dorsal margin. It affects both growth of eye disc and retinal cell differentiation.
Inclusive pages
4271-4280
ISBN/ISSN
0950-1991
Document Version
Published Version
Copyright
Copyright © 2002, Company of Biologists
Publisher
Company of Biologists
Volume
129
Peer Reviewed
yes
Issue
18
eCommons Citation
Singh, Amit; Kango-Singh, Madhuri; and Sun, Y. Henry, "Eye Suppression, A Novel Function of Teashirt, Requires Wingless Signaling" (2002). Biology Faculty Publications. 189.
https://ecommons.udayton.edu/bio_fac_pub/189
Included in
Biology Commons, Biotechnology Commons, Cell Biology Commons, Genetics Commons, Microbiology Commons, Molecular Genetics Commons
Comments
This document is provided for download in compliance with the publisher's policy on self-archiving. Permission documentation is on file.