Document Type

Article

Publication Date

2012

Publication Source

BMC Biology

Abstract

Background: Among vertebrates lens regeneration is most pronounced in newts, which have the ability to regenerate the entire lens throughout their lives. Regeneration occurs from the dorsal iris by transdifferentiation of the pigment epithelial cells. Interestingly, the ventral iris never contributes to regeneration. Frogs have limited lens regeneration capacity elicited from the cornea during pre-metamorphic stages. The axolotl is another salamander which, like the newt, regenerates its limbs or its tail with the spinal cord, but up until now all reports have shown that it does not regenerate the lens.

ISBN/ISSN

1741-7007

Document Version

Published Version

Publisher

BioMed Central

Volume

10

Issue

103

Peer Reviewed

yes

Keywords

Biomed Central Ltd, Article, Iris

Link to published version

Included in

Biology Commons

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