Title

Hydroxamic Acids as Pharmacological Agents

Document Type

Article

Publication Date

2002

Publication Source

Current Medicinal Chemistry

Abstract

A variety of hydroxamic acid derivatives have recently been touted for their potential use as inhibitors of hypertension, tumor growth, inflammation, infectious agents, asthma, arthritis, and more. Here we provide a comprehensive review of the basic medicinal chemistry and pharmacology of hydroxamic acid derivatives that have been examined as inhibitors of zinc metalloproteases, matrix metalloproteinases, leukotriene A4 hydrolases, ureases, lipoxigenases, cyclooxygenases, as well as peptide deformilases.

Inclusive pages

1631-1653

ISBN/ISSN

0929-8673

Comments

Permission documentation is on file.

Publisher

Bentham Science Publishers

Volume

9

Issue

17

Peer Reviewed

yes