Document Type
Article
Publication Date
5-2016
Publication Source
Neural Regeneration Research
Abstract
Alzheimer's disease (AD), a fatal progressive neurodegenerative disorder, has no cure to date. One of the causes of AD is the accumulation of amyloid-beta 42 (Aß42) plaques, which result in the onset of neurodegeneration. It is not known how these plaques trigger the onset of neurodegeneration. There are several animal models developed to (i) study etiology of disease, (ii) look for genetic modifiers, and (iii) identify chemical inhibitors that can block neurodegeneration and help to find cure for this disease. An insect model of Drosophila melanogaster has also provided new insights into the disease. Here we will discuss the utility of the Drosophila eye model to study Alzheimer's disease.
Inclusive pages
693-697
ISBN/ISSN
1673-5374
Document Version
Published Version
Copyright
License: Creative Commons Attribution NonCommercial Share Alike (CC-BY-NC-SA)
Publisher
Wolters Kluwer
Volume
11
Peer Reviewed
yes
Issue
5
eCommons Citation
Sarkar, Ankita; Irwin, Madison; Singh, Aditi; Riccetti, Matthew; and Singh, Amit, "Alzheimer's Disease: The Silver Tsunami of the 21st Century" (2016). Biology Faculty Publications. 191.
https://ecommons.udayton.edu/bio_fac_pub/191
Included in
Biology Commons, Biotechnology Commons, Cell Biology Commons, Genetics Commons, Microbiology Commons, Molecular Genetics Commons
Comments
This document is provided for download in compliance with the publisher's open-access policies. Permission documentation is on file.