Document Type
Article
Publication Date
2012
Publication Source
BMC Biology
Abstract
Background: Among vertebrates lens regeneration is most pronounced in newts, which have the ability to regenerate the entire lens throughout their lives. Regeneration occurs from the dorsal iris by transdifferentiation of the pigment epithelial cells. Interestingly, the ventral iris never contributes to regeneration. Frogs have limited lens regeneration capacity elicited from the cornea during pre-metamorphic stages. The axolotl is another salamander which, like the newt, regenerates its limbs or its tail with the spinal cord, but up until now all reports have shown that it does not regenerate the lens.
ISBN/ISSN
1741-7007
Document Version
Published Version
Copyright
Creative Commons Attribution Licence (CC-BY)
Publisher
BioMed Central
Volume
10
Peer Reviewed
yes
Issue
103
Keywords
Biomed Central Ltd, Article, Iris
eCommons Citation
Suetsugu-Maki, Rinako; Maki, Nobuyasu; Sumanas, Saulius; Zhu, Jie; Del Rio-Tsonis, Katia; and Tsonis, Panagiotis A., "Lens Regeneration in Axolotl: New Evidence of Developmental Plasticity" (2012). Biology Faculty Publications. 5.
https://ecommons.udayton.edu/bio_fac_pub/5
