The autophagy-related Beclin-1 protein requires the coiled-coil and BARA domains to form a homodimer with submicromolar affinity, Matthew J. Ranaghan, Michael A. Durney, Michael F. Mesleh, Patrick R. McCarren, Colin W. Garvie, Douglas S. Daniels, Kimberly L. Carey, Adam P. Skepner, Beth Levine, Jose R. Perez
Chemistry Faculty Publications

Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor, Colin W. Garvie, Cara V. Fraley, Nadine H. Elowe, Elizabeth K. Culyba, Christopher T. Lemke, Brian K. Hubbard, Virendar K. Kaushik, Douglas S. Daniels
Chemistry Faculty Publications

A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1, Matthew C. Clifton, David M. Dranow, Alison Leed, Ben Fulroth, James W. Fairman, Jan Abendroth, Kateri A. Atkins, Ellen Wallace, Dazhong Fan, Guoping Xu, Z. J. Ni, Douglas S. Daniels, John Van Drie, Guo Wei, Alex B. Burgin, Todd R. Golub, Brian K. Hubbard, Michael H. Serrano-Wu
Chemistry Faculty Publications

A Small Molecule that Binds and Inhibits the ETV1 Transcription Factor Oncoprotein, Marius C. Pop, Nicolas Stransky, Colin W. Garvie, Jean-Philippe Theurillat, Emily C. Hartman, Timothy A. Lewis, Cheng Zhong, Elizabeth K. Culyba, Fallon Lin, Douglas S. Daniels, Raymond Pagliarini, Lucienne Ronco, Angela N. Koehler, Levi A. Garraway
Chemistry Faculty Publications

Patent: Dual Function Proteins for Treating Metabolic Disorders, Brian R. Boettcher, Shari L. Caplan, Susan E. Cellitti, Douglas S. Daniels, Norio Hamamatsu, Bernhard Hubert Geierstanger, Stuart Licht, Andreas Loew, Stephen Craig Weldon
Chemistry Faculty Publications

Patent: Fusion Proteins for Treating Metabolic Disorders, Brian R. Boettcher, Shari L. Caplan, Douglas S. Daniels, Norio Hamamatsu, Stuart Licht, Stephen Craig Weldon
Chemistry Faculty Publications

Patent: Methods of Treating FGF21-Associated Disorders, Brian R. Boettcher, Shari L. Caplan, Douglas S. Daniels, Bernhard Hubert Geierstanger, Norio Hamamatsu, Stuart Licht, Andreas Loew, Stephen Craig Weldon
Chemistry Faculty Publications

New hypotheses about the structure–function of proprotein convertase subtilisin/kexin type 9: Analysis of the epidermal growth factor-like repeat A docking site using WaterMap, Robert A. Pearlstein, Qi-Ying Hu, Jing Zhou, David Yowe, Julian Levell, Bethany Dale, Virendar K. Kaushik, Douglas S. Daniels, Susan Hanrahan, Woody Sherman, Robert Abel
Chemistry Faculty Publications

Beta-peptides with improved affinity for hDM2 and hDMX, Elizabeth A. Harker, Douglas S. Daniels, Danielle A. Guarracino, Alanna S. Schepartz
Chemistry Faculty Publications

Patent: Cell-Permeable Miniature Proteins, Alanna S. Schepartz, Douglas S. Daniels, Betsy Smith
Chemistry Faculty Publications

Minimally Cationic Cell-Permeable Miniature Proteins via α-Helical Arginine Display, Betsy A. Smith, Douglas S. Daniels, Abigail E. Coplin, Gregory E. Jordan, Lynn M. McGregor, Alanna S. Schepartz
Chemistry Faculty Publications

Intrinsically Cell-Permeable Miniature Proteins Based on a Minimal Cationic PPII Motif, Alanna S. Schepartz, Douglas S. Daniels
Chemistry Faculty Publications

Biophysical and Structural Characterization of a Robust Octameric Beta-Peptide Bundle, Jessica L. Goodman, E. James Petersson, Douglas S. Daniels, Jade X. Qiu, Alanna S. Schepartz
Chemistry Faculty Publications

Biophysical Characterization of a Beta-Peptide Bundle: Comparison To Natural Proteins, E. James Petersson, Cody J. Craig, Douglas S. Daniels, Jade X. Qiu, Alanna S. Schepartz
Chemistry Faculty Publications

High-Resolution Structure of a Beta-Peptide Bundle, Douglas S. Daniels, E. James Petersson, Jade X. Qiu, Alanna S. Schepartz
Chemistry Faculty Publications

DNA binding and nucleotide flipping by the human DNA repair protein AGT, Douglas S. Daniels, Tammy T. Woo, Kieu X. Luu, David M. Noll, Neil D. Clarke, Anthony E. Pegg, John A. Tainer
Chemistry Faculty Publications

CysG Structure Reveals Tetrapyrrole-Binding Features and Novel Regulation of Siroheme Biosynthesis, M. Elizabeth Stroupe, Helen K. Leech, Douglas S. Daniels, Martin J. Warren, Elizabeth D. Getzoff
Chemistry Faculty Publications

Full-Length Archaeal Rad51 Structure and Mutants: Mechanisms for RAD51 Assembly and Control by BRCA2, David S. Shin, Luca Pellegrini, Douglas S. Daniels, Biana Yelent, Lisa Craig, Debbie Bates, David Yu, Mahmud K. Shivji, Chiharu Hitomi, Andrew S. Arvai, Niels Volkmann, Hiro Tsuruta, Tom L. Blundell, John A. Tainer
Chemistry Faculty Publications

Characterization of the Electrophile Binding Site and Substrate Binding Mode of the 26-kDa Glutathione S-transferase from Schistosoma japonicum, Rosa M. F. Cardoso, Douglas S. Daniels, Christopher M. Bruns, John A. Tainer
Chemistry Faculty Publications

Active and Alkylated Human AGT Structures: A Novel Zinc Site, Inhibitor and Extrahelical Base Binding, Douglas S. Daniels, Clifford D. Mol, Andrew S. Arvai, Sreenivas Kanugula, Anthony E. Pegg, John A. Tainer
Chemistry Faculty Publications

Mea Culpa: Formal Education and the Dis-Integrated World., Brian P. Coppola, Douglas S. Daniels
Chemistry Faculty Publications

The Role of Written and Verbal Expression in Improving Communication Skills for Students in an Undergraduate Chemistry Program, Brian P. Coppola, Douglas S. Daniels
Chemistry Faculty Publications

Structuring the Liberal (Arts) Education in Chemistry., Brian P. Coppola, Douglas S. Daniels
Chemistry Faculty Publications

I Scream, You Scream ...: A New Twist on the Liquid Nitrogen Demonstrations, Brian P. Coppola, James W. Hovick, Douglas S. Daniels
Chemistry Faculty Publications