Oncology EDGE Task Force on Prostate Cancer Outcomes: A Systematic Review of Outcome Measures for Functional Mobility

Claire Davies, Baptist Health Lexington
Genevieve Colon, University of Michigan - Flint
Hannah Geyer, University of Dayton
Lucinda Pfalzer, University of Michigan - Flint
Mary Insana Fisher, University of Dayton


Background: The medical treatment of prostate cancer results in multiple impairments in body structure and declines functional abilities, resulting in activity limitations and participation restrictions. Measurement of functional mobility is an essential outcome measure in survivorship care.

Purpose: The purpose of this systematic review is to make recommendations of the best measurement tools to assess functional mobility in men treated for prostate cancer based on psychometric properties and clinical utility.

Methods: Multiple electronic databases were searched from February to March 2014. Studies of tools used to assess functional mobility were included if they met the following criteria: reported psychometric properties, were clinically feasible methods, and were published in the English language. Each outcome measure was reviewed independently and rated by 2 reviewers separately. A single Cancer EDGE (Evaluation Database to Guide Effectiveness) Task Force Outcome Measure Rating Form was completed for each category of functional mobility assessment, and a recommendation was made using the 4-point Cancer EDGE Task Force Rating Scale.

Results: Of the original 38,373 articles found, 87 were included in this review.

Conclusion: Seven tests are highly recommended by the Oncology EDGE Task Force, 2-Minute Walk Test and 6-Minute Walk Test, 10-Meter Timed Walk, Timed Up and Go, 5 times sit to stand, based on good clinical utility and psychometric properties.