Staff in the University of Dayton Office for Research have a variety of academic and professional expertise. This collection provides a sampling of their past and present work.

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Submissions from 2017

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A Novel Dihydroxylated Derivative of Artemisinin from Microbial Transformation, Yulian Zhan, Yunshan Wu, Fangfang Xu, Yunpeng Bai, Yezhi Guan, John S. Williamson, and Bo Liu

Submissions from 2016

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Approaches by the US National Institutes of Health to Support Rigorous Scientific Research on Dietary Supplements and Natural Products, A. J. Kuszak, D. C. Hopp, John S. Williamson, Joseph M. Betz, and Barbara C. Sorkin

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The Challenge of Reproducibility and Accuracy in Nutrition Research: Resources and Pitfalls, Barbara C. Sorkin, A. J. Kuszak, John S. Williamson, D. C. Hopp, and Joseph M. Betz

Submissions from 2015

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Reduced Perylenequinone Derivatives from an Endophytic Alternaria sp. Isolated from Pinus ponderosa, Ahmed Idris, Mudasir A. Tantry, Bashir A. Ganai, Azra N. Kamili, and John S. Williamson

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Biotransformation of Artemisinin by Aspergillus niger, Yulian Zhan, Hua Liu, Yunshan Wu, Pingying Wei, Zhencheng Chen, and John S. Williamson

Submissions from 2014

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Discovery of Thienoquinolone Derivatives as Selective and ATP Non-Competitive CDK5/p25 Inhibitors by Structure-Based Virtual Screening, Arindam Chatterjee, Stephen J. Cutler, Robert J. Doerksen, Ikhlas A. Khan, and John S. Williamson

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Efficient Synthesis of 4-oxo-4,5-dihydrothieno[3,2-cc]quinoline-2-carboxylic Acid Derivatives from Aniline, Arindam Chatterjee, Stephen J. Cutler, Ikhlas A. Khan, and John S. Williamson

Submissions from 2012

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Determination of Antimalarial Compound, ARB-89 (7β-hydroxy-artemisinin carbamate) in Rat Serum by UPLC/MS/MS and its Application in Pharmacokinetics, Deepthi Pabbisetty, Anuradha Illendula, K. M. Muraleedharan, Amar G. Chittiboyina, John S. Williamson, Mitchell A. Avery, and Bonnie A. Avery

Submissions from 2010

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Isomannide and Derivatives. Chemical and Pharmaceutical Applications, Estela M.F. Muri, B. A. Abrahim, Thalita G. Barros, John S. Williamson, and Octavio A.C. Antunes

Submissions from 2009

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Novel Peptide Mimetic Inhibitors of Hepatitis C Serine Protease Derived from Isomannide, Thalita G. Barros, Sergio Pinheiro, John S. Williamson, Amilcar Tanuri, Helena S. Pereira, Rodrigo M. Brindeiro, José B. A. Neto, Octavio A.C. Antunes, and Estela M.F. Muri

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Hydroxamic Acids Designed as Inhibitors of Urease, Thalita G. Barros, John S. Williamson, Octavio A.C. Antunes, and Estela M.F. Muri

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Synthesis, Antitubercular Activity and Docking Study of Novel Cyclic Azole Substituted Diphenyl Ether Derivatives, Suvarna G. Kini, Anilchandra R. Bhat, Byron Bryant, John S. Williamson, and Franck E. Dayan

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In vitro Studies on Metabolism of Salvinorin A, Lukasz M. Kutrzeba, Vardan T. Karamyan, Robert C. Speth, John S. Williamson, and Jordan K. Zjawiony

Submissions from 2008

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7β-Hydroxy­artemisinin, Paulo B. Carvalho, Bo Liu, Yunshan Wu, John S. Williamson, and Mitchell A. Avery

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Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometric Method for the Determination of Artemisinin in Rat Serum and its Application in Pharmacokinetics, Lie Li, Deepthi Pabbisetty, Paulo Carvalho, Mitchell A. Avery, John S. Williamson, and Bonnie A. Avery

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One-Pot Synthesis of Highly Substituted Tetrahydrofurans from Activated Propargyl Alcohols using Bu3P, Yakambram Pedduri and John S. Williamson

Submissions from 2007

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Interactions of an Antimicrobial Peptide (Ac-RRWWRF-NH2) and Surfactants: Towards Antimicrobial Peptide Additives for Coatings Applications, Alicyn M. Rhoades, Douglas A. Wicks, Bruhaspathy Miriyala, and John S. Williamson

Submissions from 2006

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Synthesis of Pseudopeptides Derived from (R,R)-Tartaric Acid as Potential Inhibitors of HIV-Protease, José C. Barros, Joaquim F. M. da Silva, Alexandre R. Calazans, Amilcar Tanuri, Rodrigo de Morais Brindeiro, John S. Williamson, and Octavio A.C. Antunes

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Microbial Transformation of Artemisinin to 5-hydroxyartemisinin by Eurotium amstelodami and Aspergillus niger, Igor A. Parshikov, Bruhaspathy Miriyala, K. M. Muraleedharan, Mitchell A. Avery, and John S. Williamson

Submissions from 2005

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Pseudo-Peptides Derived from Isomannide as Potential Inhibitors of Serine Proteases, Estela M.F. Muri, Marlito Gomes Jr., Magaly Girão Albuquerque, Elaine F. F. da Cunha, Ricardo Bicca de Alencastro, John S. Williamson, and Octavio A.C. Antunes

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Phosphomolybdic Acid-Catalyzed Efficient Three-Component Reaction: A Facile Synthesis of Protected Homoallylic Amines, G. Smitha, Bruhaspathy Miriyala, and John S. Williamson

Submissions from 2004

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Chemoselective Reductive Alkylation of Ammonia with Carbonyl Compounds: Synthesis of Primary and Symmetrical Secondary Amines, Bruhaspathy Miriyala, Sukanta Bhattacharyya, and John S. Williamson

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N-t-Boc-amino Acid Esters of Isomannide: Potential Inhibitors of Serine Proteases, Estela M.F. Muri, Marlito Gomes Jr., J. S. Costa, F. L. Alencar, A. Sales Jr., Marcelo L. Bastos, Ricardo Hernández Valdés, Magaly Girão Albuquerque, Elaine F. F. da Cunha, Ricardo Bicca de Alencastro, John S. Williamson, and Octavio A.C. Antunes

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Molecular Modeling, Synthesis And Biological Evaluation of Heterocyclic Hydroxamic Acids Designed as Helicobacter Pylori Urease Inhibitors, Estela M.F. Muri, Hetal Mishra, S. M. Stein, and John S. Williamson

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Hydroxylation of 10-deoxoartemisinin to 15-hydroxy-10-deoxoartemisinin by Aspergillus niger, Igor A. Parshikov, Bruhaspathy Miriyala, Mitchell A. Avery, and John S. Williamson

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Transformation of Artemisinin by Cunninghamella elegans, Igor A. Parshikov, K. M. Muraleedharan, Mitchell A. Avery, and John S. Williamson

Submissions from 2003

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Synthesis of N-Methyl Secondary Amines, Hephzibah J. Kumpaty, John S. Williamson, and Sukanta Bhattacharyya

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An Efficient and Rapid Synthesis of β-Carboxamide Derivatives using 2,2-dimethyl-2H,4H-1,3-dioxin-4-ones by Microwave Irradiation, Bruhaspathy Miriyala and John S. Williamson

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Design and Synthesis of Heterocyclic Hydroxamic Acid Derivatives as Inhibitors of Helicobacter pylori Urease, Estela M.F. Muri, Hetal Mishra, Mitchell A. Avery, and John S. Williamson

Submissions from 2002

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Biotransformation of 10-deoxoartemisinin to its 7β-hydroxy Derivative by Mucor ramannianus, Sorele Fiaux de Medeiros, Mitchell A. Avery, Bonnie A. Avery, Selma G.F. Leite, Antonio Carlos C. Freitas, and John S. Williamson

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Experimental Investigation of an Air Microjet Array Impingement Cooling Device, John E. Leland, Rengasamy Ponnappan, and Kevin S. Klasing

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Three-Dimensional Quantitative Structure-Activity Relationship and Comparative Molecular Field Analysis of Dipeptide Hydroxamic Acid Helicobacter pylori Urease Inhibitors, Hetal Mishra, Abby L. Parrill, and John S. Williamson

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Hydroxamic Acids as Pharmacological Agents, Estela M.F. Muri, Marcelo J. Nieto, Robert D. Sindelar, and John S. Williamson

Submissions from 2001

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Correlations of Critical Froude Number for Annular-Rimming Flow in Rotating Heat Pipes, John Baker, T. Oliver, L. Lin, Rengasamy Ponnappan, and John E. Leland

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A Review of Cancer Chemopreventive Agents, Mark S. Levi, Ronald F. Borne, and John S. Williamson

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Experimental Investigation of Oscillating Heat Pipes, Lanchao Lin, Rengasamy Ponnappan, and John E. Leland

Submissions from 2000

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Axial Steady Free Surface Jet Impinging over a Flat Disk with Discrete Heat Sources, Antonio Bula, Muhammad M. Rahman, and John E. Leland

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Numerical Modeling of Conjugate Heat Transfer During Impingement of Free Liquid Jet Issuing from a Slot Nozzle, Antonio Bula, Muhammad M. Rahman, and John E. Leland

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Analysis of Transient Conjugate Heat Transfer to a Free Impinging Jet, Muhammad M. Rahman, Antonio Bula, and John E. Leland

Submissions from 1999

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Selective Monoalkylation of Ammonia: A High Throughput Synthesis of Primary Amines, Sukanta Bhattacharyya, Kurt A. Neidigh, Mitchell A. Avery, and John S. Williamson

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Free Jet Impingement Heat Transfer of a High Prandtl Number Fluid Under Conditions of Highly Varying Properties, John E. Leland and M. R. Pais

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Conjugate Heat Transfer During Free Jet Impingement of a High Prandtl Number Fluid, Muhammad M. Rahman, Antonio Bula, and John E. Leland

Submissions from 1998

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Immersion Cooling of a Simulated Electronic Chip Protruding into a Flow Channel, John E. Leland and Louis C. Chow

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Facile Preparation of N-methyl Secondary Amines by Titanium(IV) Isopropoxide-Mediated Reductive Amination of Carbonyl Compounds, Kurt A. Neidigh, Mitchell A. Avery, John S. Williamson, and Sukanta Bhattacharyya

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Test Results of Water and Methanol High-Speed Rotating Heat Pipes, Rengasamy Ponnappan, Q. He, and John E. Leland

Submissions from 1997

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Reductive Amination with Zinc Borohydride. Efficient, Safe Route to Fluorinated Benzylamines, Sukanta Bhattacharyya, Arindam Chatterjee, and John S. Williamson

Submissions from 1996

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Active Cooling of Metal Oxide Semiconductor Controlled Thyristor Using Venturi Flow, Rengasamy Ponnappan, John E. Leland, Won Soon Chang, J. E. Beam, Bick T. Nguyen, and Joseph A. Weimer

Submissions from 1995

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An Efficient, Safe and Convenient One-Step Synthesis of β-Phenethylamines via Reductive Amination Reactions Utilizing Ti(OiPr)4 and NaBH4, Sukanta Bhattacharyya, Arindam Chatterjee, and John S. Williamson

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Channel Height and Curvature Effects on Flow Boiling from an Electronic Chip, John E. Leland and Louis C. Chow

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A Solution Conformation Analysis of Forocidins I and Isoforocidins I Using NMR and Molecular Modeling, Kumar Ramu, Sachin Shringarpure, and John S. Williamson

Submissions from 1994

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The Effects of Channel Curvature and Protusion Height on Nucleate Boiling and the Critical Heat Flux of a Simulated Electronic Chip, John E. Leland

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1H-NMR and 13C-NMR Spectral Assignments of Spiramycins I and III, Kumar Ramu, Sachin Shringarpure, Steven Cooperwood, John M. Beale, and John S. Williamson

Submissions from 1993

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Forced Convection Boiling from a Nonflush Simulated Electronic Chip, John E. Leland and Louis C. Chow

Submissions from 1992

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Synthesis of a Photoreactive Taxol Side Chain, Arindam Chatterjee, John S. Williamson, Jordan K. Zjawiony, and John R. Peterson

Submissions from 1991

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High Heat Flux Cooling for Spacecraft Electronics, Louis C. Chow and John E. Leland

Submissions from 1990

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Heat-Pump-Augmented Spacecraft Heat-Rejection Systems, Robert P. Scaringe, J. A. Buckman, Lawrence R. Grzyll, E. T. Mahefkey, and John E. Leland

Submissions from 1989

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The Drag Coefficient of a Sphere in a Square Channel, Louis C. Chow, John E. Leland, J. E. Beam, and E. T. Mahefkey

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Analytical and Experimental Investigation of Melting Heat Transfer, C. Wen, John W. Sheffield, M. P. O'Dell, and John E. Leland

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O Dealkylation and Aliphatic and Aromatic Hydroxylation of 3-Methoxy-173-Estradiol by Aspergillus alliaceus, John S. Williamson, Diana Van Orden, and John P. Rosazza

Submissions from 1985

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Microbiological Hydroxylation of Estradiol: Formation of 2- and 4-hydroxyestradiol by Aspergillus alliaceus, John S. Williamson, Diana Van Orden, and John P. Rosazza