O Dealkylation and Aliphatic and Aromatic Hydroxylation of 3-Methoxy-173-Estradiol by Aspergillus alliaceus
Applied and Environmental Microbiology
Aspergillus alliaceus UI 315 was examined for its ability to metabolize 3-methoxy-17 beta-estradiol. Preparative-scale incubations with this substrate afforded good yields of 6 beta-hydroxy-17 beta-estradiol, 4-hydroxy-17 beta-estradiol, and 4,6 beta-dihydroxy-17 beta-estradiol, which were identified by high-pressure liquid chromatography, 1H and 13C nuclear magnetic resonance, and high-resolution mass spectrometry.
Copyright © 1989, American Society for Microbiology
American Society for Microbiology
Williamson, John S.; Van Orden, Diana; and Rosazza, John P., "O Dealkylation and Aliphatic and Aromatic Hydroxylation of 3-Methoxy-173-Estradiol by Aspergillus alliaceus" (1989). Office for Research Publications and Presentations. 13.