Hydroxamic Acids as Pharmacological Agents
Current Medicinal Chemistry
A variety of hydroxamic acid derivatives have recently been touted for their potential use as inhibitors of hypertension, tumor growth, inflammation, infectious agents, asthma, arthritis, and more. Here we provide a comprehensive review of the basic medicinal chemistry and pharmacology of hydroxamic acid derivatives that have been examined as inhibitors of zinc metalloproteases, matrix metalloproteinases, leukotriene A4 hydrolases, ureases, lipoxigenases, cyclooxygenases, as well as peptide deformilases.
Copyright © 2002, Bentham Science Publishers
Bentham Science Publishers
Muri, Estela M.F.; Nieto, Marcelo J.; Sindelar, Robert D.; and Williamson, John S., "Hydroxamic Acids as Pharmacological Agents" (2002). Office for Research Publications and Presentations. 20.