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Due to their unique physicochemical properties, nanomaterial (NM)-based technologies are growing exponentially in scope and economic importance. This surge is resulting in significant degrees of NM waste and increased rates of human exposure. This has created a vital need to fully understand the potential biological consequences of NM exposure, characterize resulting NM-biological interfaces and determine subsequent toxicological effects. The long-term goal of this project is to design, optimize and implement an enhanced microenvironment model (EMM) to bridge this in vitro – in vivo gap and evaluate NM characteristics, pharmacokinetic/deposition profiles and induced biological responses under physiologically relevant conditions.
Kristen Krupa Comfort
Primary Advisor's Department
Stander Symposium poster
"Design of an Enhanced Cellular Model for the Assessment and Tracking of Nanomaterials" (2019). Stander Symposium Posters. 1571.