Presenter(s)
Malabika Bhowmik, Mychaela Janzow, Tooba Ahmed Momin
Files
Download Project (910 KB)
Description
Objective: Zinc finger proteins (ZFPs) are abundant in eukaryotic cells and play critical roles in cell signalling by binding to cellular components like DNA, RNA, lipids, and other proteins. Specifically, ZFP36L1 has been identified as a regulator of RNA metabolism with antiviral activity against multiple viruses. The current study aims to examine the role of ZFP36L1 in regulating norovirus replication using murine norovirus (MNoV-1) as a model. Given that viruses often hijack the autophagy pathway to facilitate replication, we also seek to understand the relationship between ZFP36L1’s antiviral efficacy and autophagy modulation.
Publication Date
4-23-2025
Project Designation
Graduate Research
Primary Advisor
Mrigendra Rajput
Primary Advisor's Department
Biology
Keywords
Stander Symposium, College of Arts and Sciences
Institutional Learning Goals
Scholarship; Community; Scholarship
Recommended Citation
"ZFP36L1 negatively regulates autophagy to suppress murine norovirus replication" (2025). Stander Symposium Projects. 3891.
https://ecommons.udayton.edu/stander_posters/3891

Comments
3:00-4:15, Kennedy Union Ballroom