A new BODIPY photosensitizer capable of excitation within the near-infrared (NIR) region of the electromagnetic spectrum

A new BODIPY photosensitizer capable of excitation within the near-infrared (NIR) region of the electromagnetic spectrum

Presenter(s)

Emily Hardie

Comments

1:00-1:20, Kennedy Union 222

Description

Photodynamic therapy is a technique that uses and activates photosensitizing agents through the absorption of light of a certain wavelength in order to produce reactive oxygen species (ROS). When present in a cellular environment, ROS can induce cell damage and oxidative stress leading to cell death. This study introduces a NIR activated BODIPY dye capable of generating both superoxide and singlet oxygen. The synthetic route to this dye along with characterization and evaluation through 1H NMR, electronic absorption spectroscopy, and fluorescence spectroscopy is presented. Using singlet oxygen and superoxide radical quenchers, this dye shows high quantum yields for the production of ROS.

Publication Date

4-23-2025

Project Designation

Honors Thesis

Primary Advisor

Shawn M. Swavey

Primary Advisor's Department

Chemistry

Keywords

Stander Symposium, College of Arts and Sciences

Institutional Learning Goals

Scholarship

A new BODIPY photosensitizer capable of excitation within the near-infrared (NIR) region of the electromagnetic spectrum

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