The Effect of Red, Blue, and UV Light on the Inactivation of Escherichia coli for Biomedical Applications

The Effect of Red, Blue, and UV Light on the Inactivation of Escherichia coli for Biomedical Applications

Presenter(s)

Eleanor Callaghan, Anna Carollo, Ethan Potocki, Konnor Von Bargen, Audrey Zelczak

Comments

9:00-10:15, Kennedy Union Ballroom

Description

This poster provides a summary of bioengineering research performed using both visible and ultraviolet (UV) light on the inactivation of Escherichia coli DNA. Red light therapy (RLT) with a wavelength of 620–750 nm is an emerging low-level laser treatment option advertised to improve various dermatological conditions, such as eczema, psoriasis, scars, redness/inflammation, and signs of aging such as wrinkles. Red light has the ability to penetrate the inner, dermis layer of the skin, thereby promoting the production of collagen and elastin, which improve youthfulness and appearance. However, blue light therapy (BLT) devices are characterized by a shorter wavelength of 450–495 nm, which focus more superficially on the outer, epidermis layer of the skin. As a result, BLT is marketed as a treatment that kills bacteria, which can lead to conditions such as acne. The overall aim of this study was to quantify the effect of red, blue, and UV light on the inactivation of Escherichia coli DNA in vitro, through measurement of bacterial growth colonies and the level of birefringence in anisotropic cellular matrices. The results may offer insight into alternate methods for promoting prolonged shelf life, sustainable supply chains, and improved food safety measures in the grocery industry.

Publication Date

4-23-2025

Project Designation

Independent Research

Primary Advisor

Amy T. Neidhard-Doll

Primary Advisor's Department

Electrical and Computer Engineering

Keywords

Stander Symposium, School of Engineering

Institutional Learning Goals

Scholarship; Practical Wisdom; Community

The Effect of Red, Blue, and UV Light on the Inactivation of Escherichia coli for Biomedical Applications

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