Judit K. Beagle, Ph.D.
Transition metal contamination is a constant concern both in the environment and in chemical reaction mixtures. One proposed solution, is the use of peraza-crown macrocycles to selectively bind and remove transition metals. The aim of our project is to determine the novel synthesis of bis(quinoxalino) peraza-crown macrocycles for use as ligands to bind to transition metals. Our proposed molecules incorporate the rigid quinoxaline subunit into an aza-crown macrocycle which can improve binding properties. The synthesis route is novel and overcomes several limitations of the existing methods of aza-crown macrocycle preparation. We have designed the synthesis in such a way that it does not use a metal template and is general enough that new derivatives can be easily obtained.
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Chemistry | Physical Sciences and Mathematics
Farmer, Alexander J., "Synthesis of Bis(quinoxalino) Ligand for the Removal of Transition Metal Contamination" (2017). Honors Theses. 100.