Quinoxaline and its derivatives have been studied extensively for their relevant biological activity and transition metal selectivity. These compounds are commonly used for their antimicrobial, antifungal, antiparasitic activity, and relevance in the treatment of metabolic diseases . More recently, quinoxaline’s ability to inhibit gram-positive bacterial growth has been found especially in oxygen- containing compounds, yielding promising candidates to prevent cancerous tumor growth . The breadth of quinoxaline makes it a valuable tool within the research community However, its synthesis requires complex solvents, extended reaction times, and often produces a low yield. By using a microwave-assisted synthesis, this novel methodology offers high yields in a solvent-free environment, with only 5 minutes gestation.
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Horsting, Eric, "Microwave-Assisted Synthesis of Quinoxaline Derivatives" (2022). Honors Theses. 357.