Honors Theses

Title

Investigating the Role of the Nervous System in Limb Regeneration: A Proteomics Analysis

Advisor

Pothitos Pitychoutis

Department

Biology

Publication Date

4-1-2022

Document Type

Honors Thesis

Abstract

Regeneration is a biological ability belonging to a small subset of vertebrates including the axolotl (i.e., Ambystoma mexicanum), an amphibian that can regenerate its limbs as well as other organs such as the heart and the brain, throughout its lifespan. While it is known that the nerves play a critical role in promoting limb regeneration, the potential implication of other nervous system components is largely unknown. Proteomics screening approaches were implemented in our lab to compare protein expression patterns at various time-points into the regeneration program following limb amputation. In the context of the current honors thesis project, we identified proteins that are upregulated and/or downregulated throughout limb regeneration program, and we are currently working towards exposing novel protein networks that are activated during this fascinating process.

Permission Statement

This thesis is not available in the repository or through interlibrary loan; to view it in person, visit the University Archives by telephone at 937-229-4256 or via email at archives@udayton.edu.

Keywords

Undergraduate research

Disciplines

Biology

This document is currently not available here.


Share

COinS