Title

Biotransformation of 10-deoxoartemisinin to its 7β-hydroxy Derivative by Mucor ramannianus

Document Type

Article

Publication Date

6-2002

Publication Source

Biotechnology Letters

Abstract

10-Deoxoartemisinin at 0.2 mg ml−1 medium was transformed to 7β-hydroxy deoxoartemisinin by Mucor ramannianus growing on sucrose, 20 g l−1, and peptone, 10 g l−1, at pH 4 and 26 °C. The yield of product was increased from 16% to 45% by selecting optimal culture conditions using a 25−2 factorial design.

Inclusive pages

937–941

ISBN/ISSN

0141-5492

Comments

Permission documentation is on file.

Publisher

Springer

Volume

24

Issue

11

Peer Reviewed

yes