Synthesis of a Photoreactive Taxol Side Chain

Author(s)

Arindam Chatterjee, University of Mississippi
John S. Williamson, University of DaytonFollow
Jordan K. Zjawiony, University of Mississippi
John R. Peterson, University of Mississippi

Document Type

Article

Publication Date

1992

Publication Source

Bioorganic & Medicinal Chemistry Letters

Abstract

The photoreactive taxol side chain, (2R,3S)-(−)-N-(4′-azido-benzoyl-3-phenylisoserine methyl ester (6), was prepared in four steps from (2R,3R)-(+)-methyl 3-phenylglycidate (2).

In an effort to synthesize a photoreactive taxol derivative (7), the side chain (2R,3S)-(−)-N-(4′-azido-benzoyl-3-phenylisoserine methyl ester (6), was prepared in four steps from (2R,3R)-(+)-methyl 3-phenylglycidate (2).

Inclusive pages

91-94

ISBN/ISSN

0960-894X

Comments

Permission documentation is on file.

Copyright

Copyright © 1992, Elsevier

Publisher

Elsevier

Volume

2

Issue

1

Peer Reviewed

yes

eCommons Citation

Chatterjee, Arindam; Williamson, John S.; Zjawiony, Jordan K.; and Peterson, John R., "Synthesis of a Photoreactive Taxol Side Chain" (1992). Office for Research Publications and Presentations. 9.
https://ecommons.udayton.edu/ofr_pub/9