Title

Synthesis of a Photoreactive Taxol Side Chain

Document Type

Article

Publication Date

1992

Publication Source

Bioorganic & Medicinal Chemistry Letters

Abstract

The photoreactive taxol side chain, (2R,3S)-(−)-N-(4′-azido-benzoyl-3-phenylisoserine methyl ester (6), was prepared in four steps from (2R,3R)-(+)-methyl 3-phenylglycidate (2).

In an effort to synthesize a photoreactive taxol derivative (7), the side chain (2R,3S)-(−)-N-(4′-azido-benzoyl-3-phenylisoserine methyl ester (6), was prepared in four steps from (2R,3R)-(+)-methyl 3-phenylglycidate (2).

Inclusive pages

91-94

ISBN/ISSN

0960-894X

Comments

Permission documentation is on file.

Publisher

Elsevier

Volume

2

Issue

1

Peer Reviewed

yes


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