Document Type
Article
Publication Date
1-28-2013
Publication Source
Molecular Vision
Abstract
Purpose: Notophthalmus viridescens, the red-spotted newt, possesses tremendous regenerative capabilities. Among the tissues and organs newts can regenerate, the lens is regenerated via transdifferentiation of the pigment epithelial cells of the dorsal iris, following complete removal (lentectomy). Under normal conditions, the same cells from the ventral iris are not capable of regenerating. This study aims to further understand the initial signals of lens regeneration.
Inclusive pages
135-145
ISBN/ISSN
1090-0535
Document Version
Published Version
Copyright
Creative Commons Attribution License (CC-BY)
Publisher
Molecular Vision
Volume
19
Peer Reviewed
yes
Keywords
Molecular Vision, Article, Oxidative Stress, Adult Newt, Tool, Dedifferentiation, Complex, Cells
eCommons Citation
Sousounis, Konstantinos; Michel, Christian S.; Bruckskotten, Marc; Maki, Nobuyasu; Borchardt, Thilo; Braun, Thomas; Looso, Mario; and Tsonis, Panagiotis A., "A Microarray Analysis of Gene Expression Patterns During Early Phases of Newt Lens Regeneration" (2013). Biology Faculty Publications. 13.
https://ecommons.udayton.edu/bio_fac_pub/13