Dorso-Ventral Asymmetric Functions of teashirt in Drosophila Eye Development Depend on Spatial Cues Provided by Early DV Patterning Genes

Author(s)

Amit Singh, University of DaytonFollow
Madhuri Kango-Singh, University of DaytonFollow
Kwang-Wook Choi, Baylor College of Medicine
Y. Henry Sun, Academia Sinica

Document Type

Article

Publication Date

4-2004

Publication Source

Mechanisms of Development

Abstract

The teashirt (tsh) gene has dorso-ventral (DV) asymmetric functions in Drosophila eye development: promoting eye development in dorsal and suppressing eye development in ventral by Wingless mediated Homothorax (HTH) induction [Development 129 (2002) 4271]. We looked for DV spatial cues required by tsh for its asymmetric functions. The dorsal Iroquois-Complex (Iro-C) genes and Delta (Dl) are required and sufficient for the tsh dorsal functions. The ventral Serrate (Ser), but not fringe (fng) or Lobe (L), is required and sufficient for the tsh ventral function. We propose that DV asymmetric function of tsh represents a novel tier of DV pattern regulation, which takes place after the spatial expression patterns of early DV patterning genes are established in the eye.

Inclusive pages

365–370

ISBN/ISSN

0925-4773

Comments

Permission documentation is on file.

Copyright

Copyright © 2004, Elsevier

Publisher

Elsevier

Volume

121

Peer Reviewed

yes

Issue

4

eCommons Citation

Singh, Amit; Kango-Singh, Madhuri; Choi, Kwang-Wook; and Sun, Y. Henry, "Dorso-Ventral Asymmetric Functions of teashirt in Drosophila Eye Development Depend on Spatial Cues Provided by Early DV Patterning Genes" (2004). Biology Faculty Publications. 148.
https://ecommons.udayton.edu/bio_fac_pub/148