A Glimpse into Dorso-Ventral Patterning of the Drosophila Eye

Author(s)

Amit Singh, University of DaytonFollow
Meghana Tare, University of Dayton
Oorvashi Roy Puli, University of DaytonFollow
Madhuri Kango-Singh, University of DaytonFollow

Document Type

Article

Publication Date

1-2012

Publication Source

Developmental Dynamics

Abstract

During organogenesis in all multi-cellular organisms, axial patterning is required to transform a single layer organ primordium into a three-dimensional organ. The Drosophila eye model serves as an excellent model to study axial patterning. Dorso-ventral (DV) axis determination is the first lineage restriction event during axial patterning of the Drosophila eye. The early Drosophila eye primordium has a default ventral fate, and the dorsal eye fate is established by onset of dorsal selector gene pannier (pnr) expression in a group of cells on the dorsal eye margin. The boundary between dorsal and ventral compartments called the equator is the site for Notch (N) activation, which triggers cell proliferation and differentiation. This review will focus on (1) chronology of events during DV axis determination; (2) how early division of eye into dorsal and ventral compartments contributes towards the growth and patterning of the fly retina; and (3) functions of DV patterning genes.

Inclusive pages

69–84

ISBN/ISSN

1058-8388

Comments

Permission documentation is on file.

Copyright

Copyright © 2011, Wiley Periodicals

Publisher

Wiley Periodicals

Volume

241

Peer Reviewed

yes

Issue

1

eCommons Citation

Singh, Amit; Tare, Meghana; Puli, Oorvashi Roy; and Kango-Singh, Madhuri, "A Glimpse into Dorso-Ventral Patterning of the Drosophila Eye" (2012). Biology Faculty Publications. 163.
https://ecommons.udayton.edu/bio_fac_pub/163