Eye Suppression, A Novel Function of Teashirt, Requires Wingless Signaling

Author(s)

Amit Singh, University of DaytonFollow
Madhuri Kango-Singh, University of DaytonFollow
Y. Henry Sun, Academia Sinica

Document Type

Article

Publication Date

9-2002

Publication Source

Development

Abstract

Teashirt (tsh) encodes a Drosophila zinc-finger protein. Misexpression of tsh has been shown to induce ectopic eye formation in the antenna. We report that tsh can suppress eye development. This novel function of tsh is due to the induction of homothorax (hth), a known repressor of eye development, and requires Wingless (WG) signaling. Interestingly, tsh has different functions in the dorsal and ventral eye, suppressing eye development close to the ventral margin, while promoting eye development near the dorsal margin. It affects both growth of eye disc and retinal cell differentiation.

Inclusive pages

4271-4280

ISBN/ISSN

0950-1991

Document Version

Published Version

Comments

This document is provided for download in compliance with the publisher's policy on self-archiving. Permission documentation is on file.

Copyright

Copyright © 2002, Company of Biologists

Publisher

Company of Biologists

Volume

129

Peer Reviewed

yes

Issue

18

eCommons Citation

Singh, Amit; Kango-Singh, Madhuri; and Sun, Y. Henry, "Eye Suppression, A Novel Function of Teashirt, Requires Wingless Signaling" (2002). Biology Faculty Publications. 189.
https://ecommons.udayton.edu/bio_fac_pub/189