Document Type
Article
Publication Date
2016
Publication Source
Advances in Applied Microbiology
Abstract
Bacterial enteric pathogens are responsible for a tremendous amount of foodborne illnesses every year through the consumption of contaminated food products. During their transit from contaminated food sources to the host gastrointestinal tract, these pathogens are exposed and must adapt to fluctuating oxygen levels to successfully colonize the host and cause diseases. However, the majority of enteric infection research has been conducted under aerobic conditions. To raise awareness of the importance in understanding the impact of oxygen, or lack of oxygen, on enteric pathogenesis, we describe in this review the metabolic and physiological responses of nine bacterial enteric pathogens exposed to environments with different oxygen levels. We further discuss the effects of oxygen levels on virulence regulation to establish potential connections between metabolic adaptations and bacterial pathogenesis. While not providing an exhaustive list of all bacterial pathogens, we highlight key differences and similarities among nine facultative anaerobic and microaerobic pathogens in this review to argue for a more in-depth understanding of the diverse impact oxygen levels have on enteric pathogenesis.
Inclusive pages
179-204
ISBN/ISSN
0065-2164
Document Version
Postprint
Copyright
Copyright © 2016, Elsevier
Publisher
Elsevier
Volume
95
Peer Reviewed
yes
eCommons Citation
Wallace, Nathan; Zani, Ashley N.; Abrams, Elizabeth A.; and Sun, Yvonne, "The Impact of Oxygen on Bacterial Enteric Pathogens" (2016). Biology Faculty Publications. 245.
https://ecommons.udayton.edu/bio_fac_pub/245
Included in
Biology Commons, Biotechnology Commons, Cell Biology Commons, Genetics Commons, Microbiology Commons, Molecular Genetics Commons
Comments
© 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/.
Permission documentation on file.