Document Type
Article
Publication Date
2006
Publication Source
Molecular Vision
Abstract
Purpose: It has been shown that after extracapsular lens removal by anterior capsulotomy in the mouse, the lens can be regenerated. However, as the capsular bag is filled with fibers, epithelial to mesenchymal transition (EMT), an event which is common after cataract surgery as well, takes place during early stages. This study, using a unique mouse model, was undertaken to identify novel regulators and networks in order to more clearly understand secondary cataracts at the molecular level.
Inclusive pages
422-440
ISBN/ISSN
1090-0535
Document Version
Published Version
Copyright
Creative Commons Attribution, Non-Commercial, No Derivative Works License 3.0 (CC-BY-NC-ND)
Publisher
Molecular Vision
Volume
12
Peer Reviewed
yes
Issue
49
Keywords
Molecular Vision, Article, Sequence Tag Analysis, Posterior Capsule Opacification, Neibank Project, Cells, Transdifferentiation, Cataract, Model, Beta, Mice, Identification
eCommons Citation
Medvedovic, Mario; Tomlinson, Craig R.; Call, Mindy Kay; Grogg, Matthew; and Tsonis, Panagiotis A., "Gene Expression and Discovery During Lens Regeneration in Mouse: Regulation of Epithelial to Mesenchymal Transition and Lens Differentiation" (2006). Biology Faculty Publications. 8.
https://ecommons.udayton.edu/bio_fac_pub/8
