Preparation and Characterization of Some Substituted Benzyl N-nitrosocarbamates Containing an N-2-(methylthio)ethyl or a Bis(2-aminoethyl)sulfide Functionality

Author(s)

Satya Venkata, University of Dayton
Eric Shamo, University of Dayton
Vladimir Benin, University of DaytonFollow

Document Type

Article

Publication Date

2009

Publication Source

Synthetic Communications

Abstract

The synthesis and characterization of some substituted benzyl N-nitrosocarbamates with an N-2-(methylthio)ethyl or a bis(2-aminoethyl)sulfide functionality is reported, as a part of a long-term goal to design and prepare novel photolabile structures that could be used as substances for controlled release of alkylating and/or crosslinking agents. The synthesis was accomplished by reaction of benzyl chloroformates with the corresponding amines, resulting in the preparation of carbamates. The latter were subsequently nitrosated, utilizing two different N-nitrosation methods, to yield the target structures.

Inclusive pages

1406–1414

ISBN/ISSN

0039-7911

Document Version

Postprint

Comments

The document available for download is the authors' accepted manuscript, posted here in compliance with the publisher's policy on self-archiving.

Some differences may exist between this version and the publisher's version; as such, researchers wishing to quote directly from it are advised to consult the version of record, available at many libraries or from the publisher.

Permission documentation is on file.

Copyright

Copyright © 2009, Taylor & Francis

Publisher

Taylor & Francis

Volume

39

Peer Reviewed

yes

Issue

8

eCommons Citation

Venkata, Satya; Shamo, Eric; and Benin, Vladimir, "Preparation and Characterization of Some Substituted Benzyl N-nitrosocarbamates Containing an N-2-(methylthio)ethyl or a Bis(2-aminoethyl)sulfide Functionality" (2009). Chemistry Faculty Publications. 7.
https://ecommons.udayton.edu/chm_fac_pub/7