Document Type
Article
Publication Date
6-29-2025
Publication Source
ChemistryOpen
Abstract
Magnetic nanoparticles (MNPs) are multifunctional materials with superparamagnetic properties and tunable surface chemistries, making them valuable across diverse fields, such as biomedicine, environmental remediation, and agriculture. This review examines recent advancements in MNP synthesis, encompassing chemical, physical, and environmentally friendly methods while highlighting improvements in size, morphology, and composition control that enhance application-specific performance and environmental sustainability. The review discusses various architectures, including single-core, core–shell, hybrid composites, and stimuli–responsive systems, with an emphasis on their stability, scalability, and functionalization potential. In biomedical applications, MNPs show promise in targeted drug delivery, magnetic hyperthermia, and magnetic resonance imaging contrast enhancement, where biocompatibility, often achieved through green synthesis, is critical. In agriculture, iron oxide MNPs (Fe3O4) have been utilized as nanofertilizers and growth promoters, demonstrating the ability to improve seed germination, chlorophyll content, and root development in crops, such as maize and tomatoes, without exhibiting phytotoxicity. Despite these promising results, challenges remain in large-scale production, reproducibility, and regulatory acceptance. This review highlights the pivotal role of MNPs in advancing nanotechnology-driven solutions across the life sciences. Their evolving synthesis techniques, multifunctional properties, and cross-sector applications position MNPs as key enablers of next-generation technologies in diagnostics, therapeutics, environmental monitoring, and sustainable agriculture.
ISBN/ISSN
ISSN: 2191-1363; eISSN: 2191-1363
Document Version
Published Version
Copyright
© 2025 The Author(s). ChemistryOpen is published by Wiley-VCH GmbH.
Publisher
Wiley-VCH GmbH
Peer Reviewed
yes
Sponsoring Agency
NIFA Grant no. 2023-67017-40045 from the U.S. Department of Agriculture’s National Institute of Food and Agriculture
eCommons Citation
Chand, Kishore and Vasquez, Erick Salvador, "Magnetic Nanoparticles: Synthesis and Applications in Life Sciences" (2025). Chemical and Materials Engineering Faculty Publications. 250.
https://ecommons.udayton.edu/cme_fac_pub/250
COinS

Comments
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. DOI: 10.1002/open.202500214