Fluorescent Composite Scaffolds Made of Nanodiamonds/Polycaprolactone
Document Type
Article
Publication Date
11-2015
Publication Source
Chemical Physics Letters
Abstract
Polycaprolactone (PCL) has been widely studied for biological applications. Biodegradable PCL fibrous scaffold can work as an appropriate substrate for tissue regeneration. In this letter, fluorescent nanodiamonds (FNDs) were prepared after surface passivation with octadecylamine. The FNDs were then mixed with PCL polymer and subsequently electrospun into FNDs/PCL fibrous scaffolds. The obtained scaffolds not only exhibited photoluminescence, but also showed reinforced mechanical strength. Toxicity study indicated FNDs/PCL scaffolds were nontoxic. This biocompatible fluorescent composite fibrous scaffold can support in vitro cell growth and also has the potential to act as an optical probe for tissue engineering application in vitro and in vivo.
Inclusive pages
123–128
ISBN/ISSN
0009-2614
Copyright
Copyright © 2015, Elsevier
Publisher
Elsevier
Volume
641
Peer Reviewed
yes
eCommons Citation
Cao, Li; Hou, Yanwen; Lafdi, Khalid; and Urmey, Kirk, "Fluorescent Composite Scaffolds Made of Nanodiamonds/Polycaprolactone" (2015). Chemical and Materials Engineering Faculty Publications. 28.
https://ecommons.udayton.edu/cme_fac_pub/28
