Hydroxamic Acids Designed as Inhibitors of Urease
Letters in Drug Design & Discovery
Urease is an enzyme responsible for the hydrolysis of urea into ammonia and carbamate. Humans infected by urease are exposed to a risk of chronic gastritis or cancer. Urease inhibitors have attracted a great deal of attention for their potential as new anti-ulcer drugs. Here, we describe the synthesis of series of hydroxamic acid compounds designed as inhibitors of urease.
Copyright © 2009, Bentham Science Publishers
Bentham Science Publishers
Barros, Thalita G.; Williamson, John S.; Antunes, Octavio A.C.; and Muri, Estela M.F., "Hydroxamic Acids Designed as Inhibitors of Urease" (2009). Office for Research Publications and Presentations. 37.