Extracellular biofilm polysaccharides-mediated antibiotic resistance of Pseudomonas aeruginosa

Extracellular biofilm polysaccharides-mediated antibiotic resistance of Pseudomonas aeruginosa

Presenter(s)

Celeste Claire Bergman

Description

High density surface-attached growth of bacteria are called biofilms. This bacterial community secrete extracellular matrix materials, of which the major components are polysaccharides. The polysaccharides serve as adhesion molecules as well as a protective barrier against antibiotics and other antimicrobial compounds. Pseudomonas aeruginosa is an opportunistic pathogen, and its propensity to grow biofilms in infected sites causes serious medical problems, often untreatable due to their antibiotic resistance properties. The two major biofilm polysaccharides of P. aeruginosa are the PEL and PSL polysaccharides. In this project, we show the relationships between antibiotic resistance and PEL/PSL polysaccharides of P. aeruginosa biofilms.

Publication Date

4-18-2018

Project Designation

Honors Thesis

Primary Advisor

Yasuhiko Irie

Primary Advisor's Department

Biology

Keywords

Stander Symposium project

Extracellular biofilm polysaccharides-mediated antibiotic resistance of Pseudomonas aeruginosa

Share

COinS