Extracellular biofilm polysaccharides-mediated antibiotic resistance of Pseudomonas aeruginosa
Celeste Claire Bergman
High density surface-attached growth of bacteria are called biofilms. This bacterial community secrete extracellular matrix materials, of which the major components are polysaccharides. The polysaccharides serve as adhesion molecules as well as a protective barrier against antibiotics and other antimicrobial compounds. Pseudomonas aeruginosa is an opportunistic pathogen, and its propensity to grow biofilms in infected sites causes serious medical problems, often untreatable due to their antibiotic resistance properties. The two major biofilm polysaccharides of P. aeruginosa are the PEL and PSL polysaccharides. In this project, we show the relationships between antibiotic resistance and PEL/PSL polysaccharides of P. aeruginosa biofilms.
Primary Advisor's Department
Stander Symposium project
"Extracellular biofilm polysaccharides-mediated antibiotic resistance of Pseudomonas aeruginosa" (2018). Stander Symposium Projects. 1322.