Understanding the development of antibiotic resistance in Listeria monocytogenes

Understanding the development of antibiotic resistance in Listeria monocytogenes

Presenter(s)

Andrea Marie Vietti

Description

Bacterial antibiotic resistance is on an alarming rise worldwide, thus posing an urgent threat to human health. The rise in antibiotic resistance can be attributed to the overuse and misuse of antibiotics in both the healthcare and agricultural industries. In order to address this concern, this research is aimed to identify environmental conditions that may lead to the development of antibiotic resistance in Listeria monocytogenes. Listeria is a foodborne pathogen capable of causing the disease listeriosis especially in immunocompromised populations. Although infected individuals are treated with antibiotics, an alarmingly high mortality rate of 20 percent still persists; thus, it is important to further understand the impact various environmental conditions may have on the development of antibiotic resistance. Various genetic mutants of Listeria were exposed to antibiotics commonly used to treat Listeria infections, and the susceptibility to these antibiotics was observed under environments with and without oxygen.

Publication Date

4-24-2019

Project Designation

Honors Thesis

Primary Advisor

Yvonne Y. Sun

Primary Advisor's Department

Biology

Keywords

Stander Symposium project

Understanding the development of antibiotic resistance in Listeria monocytogenes

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