Drosophila Tumor Mosaic Models To Study Intercellular Interactions

Drosophila Tumor Mosaic Models To Study Intercellular Interactions

Authors

    Presenter(s)

    Minh T Ho

    Files

    Description

    Drosophila is a powerful genetic model system to study cancer. In patients, a small number of mutations accumulate in cells which change their growth characteristics and eventually lead to formation of tumors. These tumors are clonal in origin, meaning the cancer arose from proliferation of a single rogue cell. We have developed similar "clonal" cancer models in Drosophila wing and brain to study how tumor cells interact among each other and with their neighbors. My goal is to develop tools to manipulate either the tumor or the normal neighboring cells and test the effect of tumor growth and progression.

    Publication Date

    4-24-2019

    Project Designation

    Honors Thesis

    Primary Advisor

    Madhuri Kango-Singh

    Primary Advisor's Department

    Biology

    Keywords

    Stander Symposium project

    Drosophila Tumor Mosaic Models To Study Intercellular Interactions

    Share

    COinS