Drosophila Tumor Mosaic Models To Study Intercellular Interactions

Drosophila Tumor Mosaic Models To Study Intercellular Interactions

Presenter(s)

Minh T Ho

Description

Drosophila is a powerful genetic model system to study cancer. In patients, a small number of mutations accumulate in cells which change their growth characteristics and eventually lead to formation of tumors. These tumors are clonal in origin, meaning the cancer arose from proliferation of a single rogue cell. We have developed similar "clonal" cancer models in Drosophila wing and brain to study how tumor cells interact among each other and with their neighbors. My goal is to develop tools to manipulate either the tumor or the normal neighboring cells and test the effect of tumor growth and progression.

Publication Date

4-24-2019

Project Designation

Honors Thesis

Primary Advisor

Madhuri Kango-Singh

Primary Advisor's Department

Biology

Keywords

Stander Symposium project

Drosophila Tumor Mosaic Models To Study Intercellular Interactions

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