Presenter(s)

Abigail Elizabeth Wink

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Description

Antimicrobial compounds play an integral role in modern medicine due to their drug resistant qualities that pose as a serious public health issue. The demand for discovering new antibiotics and exploring various alternative methods of infection treatment has increased due to the prevalence of antibiotic resistance. As outlined by the CDC, various pathogens such as drug-resistant Neisseria gonorrhoeae and Carbapenem-resistant Acinetobacter are recognized as an urgent threat due to their antibiotic resistance (CDC, 2019). Thus, the goal of this research is to further identify antibiotics isolated from soil samples on the UD campus to determine if they produce antibiotic compounds in the presence of ESKAPE pathogens. Zones of inhibition were found to be produced in the presence of Pseudomonas putida, Bacillus subtilis, and Escherichia coli which demonstrated antimicrobial activity. Biochemical assays, such as catalase testing and gram staining were used to help identify isolate species. Chemical extractions were utilized to determine if the bacteria extracted from the isolates exhibit antimicrobial activity. Isolating antimicrobial compounds is imperative in the healthcare setting, as drug resistance determines the efficacy of antibiotics.

Publication Date

4-22-2021

Project Designation

Independent Research

Primary Advisor

Jessica Elizabeth Geyer, Yvonne Y. Sun

Primary Advisor's Department

Biology

Keywords

Stander Symposium project, College of Arts and Sciences

United Nations Sustainable Development Goals

Good Health and Well-Being

Antimicrobial Compounds Extracted from Soil Isolates

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