Assessment of Aggressive Behavior in a Transgenic Mouse Model

Assessment of Aggressive Behavior in a Transgenic Mouse Model

Presenter(s)

Kiara Eileen Bahamonde, Ben Klocke

Comments

Presentation: 9:00 a.m.-10:15 a.m., Kennedy Union Ballroom

Description

The Tube Dominance Test has been widely used to assess social dominance, aggression, and social hierarchy in mice. The purpose of our study was to determine if the Tube Dominance Test can be used to identify aggression and social dominance in transgenic mice that lack a specific calcium regulatory protein. To test this hypothesis wild type and knockout mice of both sexes were habituated with the clear tube and handled for three days. For five days, the mice were trained to pass through the tube. For testing, two mice meet in the middle of the clear tube. Due to limited space within the tube, only one mouse can pass at a time; therefore, one mouse must submit to the other. Preliminary analyses are currently being conducted using this behavioral assay to assess aggression levels in this mouse strain.

Publication Date

4-20-2022

Project Designation

Independent Research

Primary Advisor

Pothitos Pitychoutis

Primary Advisor's Department

Biology

Keywords

Stander Symposium project, College of Arts and Sciences

United Nations Sustainable Development Goals

Good Health and Well-Being

Assessment of Aggressive Behavior in a Transgenic Mouse Model

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