Investigating the Role of Neural Stem Cells in Aggressive Gliomas

Investigating the Role of Neural Stem Cells in Aggressive Gliomas

    Presenter(s)

    Sadie Mae Salamone

    Comments

    Presentation: 1:15 p.m.-2:30 p.m., Kennedy Union Ballroom

    This project reflects research conducted as part of a course project designed to give students experience in the research process.

    Course: MED 480

    Description

    Glioblastoma Multiforme (GBM) is an extremely aggressive type of brain cancer with no ultimate cure and a high mortality rate. These tumors form and metastasize quickly, making this specific type of cancer difficult to treat and fatal for almost all who receive this diagnosis. This study will explore the growth patterns of GBM tumors using the model organism of Drosophila melanogaster, which is the common fruit fly. A genetic cross between two genotypically different flies is used to produce the GBM tumor. These genotypes represent mutations in genes commonly found mutated in human patients, thus findings from this work may be relevant to understanding early changes in glial cells in human glia as well. The findings from this study will allow for a better understanding of the growth patterns of GBM tumors and hopefully aid in finding a treatment method for this aggressive type of cancer. The purpose of this poster is to discuss the dangers of GBM, discuss the fruit fly as a model organism, describe completed and planned steps of this investigation and explore the benefits and possible ramifications that may arise in this study.

    Publication Date

    4-20-2022

    Project Designation

    Course Project

    Primary Advisor

    Madhuri Kango-Singh, Kathleen C. Scheltens

    Primary Advisor's Department

    Biology

    Keywords

    Stander Symposium project, College of Arts and Sciences

    United Nations Sustainable Development Goals

    Quality Education

    Investigating the Role of Neural Stem Cells in Aggressive Gliomas

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