Exploring the Role of the Nervous System in Limb Regeneration

Exploring the Role of the Nervous System in Limb Regeneration

Authors

    Presenter(s)

    Ben Klocke, Jason Tornes

    Comments

    Presentation: 9:00 a.m.-10:15 a.m., Kennedy Union Ballroom

    External collaborators:
    Dr. Mario Looso at the Max Planck Institute for Heart and Lung Research and Dr. Katia Del-Rio Tsonis at Miami University

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    Description

    Regeneration is a biological ability belonging to a small subset of vertebrates including the axolotl, an amphibian that can regenerate its limbs upon amputation. While it is known that the nerves play a critical role in promoting limb regeneration, the potential implication of other nervous system components is largely unknown. Proteomics screening approaches were implemented to compare protein expression data at various time-points into the limb regeneration program following amputation. In this presentation we identified proteins that are upregulated and/or downregulated throughout limb regeneration, and are currently working towards exposing novel protein networks that are activated during this fascinating process.

    Publication Date

    4-20-2022

    Project Designation

    Honors Thesis

    Primary Advisor

    Pothitos Pitychoutis

    Primary Advisor's Department

    Biology

    Keywords

    Stander Symposium project, College of Arts and Sciences

    United Nations Sustainable Development Goals

    Good Health and Well-Being

    Exploring the Role of the Nervous System in Limb Regeneration

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