Exploring the Role of the Nervous System in Limb Regeneration
Presenter(s)
Ben Klocke, Jason Tornes
Files
Description
Regeneration is a biological ability belonging to a small subset of vertebrates including the axolotl, an amphibian that can regenerate its limbs upon amputation. While it is known that the nerves play a critical role in promoting limb regeneration, the potential implication of other nervous system components is largely unknown. Proteomics screening approaches were implemented to compare protein expression data at various time-points into the limb regeneration program following amputation. In this presentation we identified proteins that are upregulated and/or downregulated throughout limb regeneration, and are currently working towards exposing novel protein networks that are activated during this fascinating process.
Publication Date
4-20-2022
Project Designation
Honors Thesis
Primary Advisor
Pothitos Pitychoutis
Primary Advisor's Department
Biology
Keywords
Stander Symposium project, College of Arts and Sciences
United Nations Sustainable Development Goals
Good Health and Well-Being
Recommended Citation
"Exploring the Role of the Nervous System in Limb Regeneration" (2022). Stander Symposium Projects. 2413.
https://ecommons.udayton.edu/stander_posters/2413
Comments
Presentation: 9:00 a.m.-10:15 a.m., Kennedy Union Ballroom
External collaborators:
Dr. Mario Looso at the Max Planck Institute for Heart and Lung Research and Dr. Katia Del-Rio Tsonis at Miami University