Piperazine-Based Metallopolymers for Bioengineering Applications

Piperazine-Based Metallopolymers for Bioengineering Applications

Presenter(s)

Jessica Schneider

Comments

Presentation: 2:00-2:20 p.m., Kennedy Union 222

Description

Engineering realistic and functional tissue models presents promising possibilities in drug discovery and other biomedical research. A novel polymer with potential applications in biomedical studies was developed. I report the first synthesis and characterization (with NMR, IR, GPC, UV–vis spectroscopy, and thermal analysis) of two thermoplastic poly(alkyl piperazine succinate) diols with either propyl or hexyl alkane chains bridging the piperazines. These polyester diols were chain extended with hexamethylene diisocyanate to create highly amorphous polyester urethane thermoplastic polymers. Ru(III) and Fe(III) was then successfully coordinated with these polymers, producing a total of four different metallopolymers. The crosslinking of these complexes introduces degradative properties to the polymer, which could be valuable in biomedical studies.

Publication Date

4-19-2023

Project Designation

Honors Thesis

Primary Advisor

Justin Biffinger

Primary Advisor's Department

Chemistry

Keywords

Stander Symposium, College of Arts and Sciences

Institutional Learning Goals

Scholarship

Piperazine-Based Metallopolymers for Bioengineering Applications

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