Synthesis and characterization of BODIPY single molecule probe for protein conjugation

Synthesis and characterization of BODIPY single molecule probe for protein conjugation

Authors

    Presenter(s)

    Amy Hess, Erin Stuczynski

    Comments

    Presentation: 9:00-10:15 a.m., Kennedy Union Ballroom

    Files

    Description

    A single molecule 4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) dye designed toconjugate to the peripheral amines of proteins have been synthesized. The syntheticroute taken toward this dye along with characterization by 1 H NMR will be described.This dye offers extraordinary absorption and emission properties within the visibleregion of the electromagnetic spectrum. Details of its spectroscopic properties alongwith first attempts to conjugate this dyes to proteins will be presented.

    Publication Date

    4-19-2023

    Project Designation

    Independent Research

    Primary Advisor

    Shawn Swavey

    Primary Advisor's Department

    Chemistry

    Keywords

    Stander Symposium, College of Arts and Sciences

    Institutional Learning Goals

    Scholarship

    Synthesis and characterization of BODIPY single molecule probe for protein conjugation

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