Novel role of miRNA-137 in Drosophila eye development

Novel role of miRNA-137 in Drosophila eye development

Authors

Presenter(s)

Rad Radhika Padma

Comments

Presentation: 9:20-9:40, Kennedy Union 312

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Description

During organogenesis various players including genes non-coding RNAs like microRNA (miRNA) are involved in differentiation and development. miRNA are involved in post- transcriptional regulation of gene expression in a tissue-specific manner and thereby fine tune the expression of their target gene(s). Therefore, miRNAs play a crucial role in regulation of the cell fate and differentiation during development. In a forward genetic screen, we identified a miRNA which exhibits reduced eye phenotype upon overexpression in the developing eye. Here, we present our characterization of the role of this new miRNA (miR-137) in growth and development of an eye-antennal imaginal disc of Drosophila. Our results illustrate the novel role of miR-137 in eye development and growth. The results from our studies on molecular characterization of the role of this miR-137 during eye development will be presented.

Publication Date

4-17-2024

Project Designation

Independent Research

Primary Advisor

Madhuri Kango-Singh, Amit Singh

Primary Advisor's Department

Biology

Keywords

Stander Symposium, College of Arts and Sciences

Novel role of miRNA-137 in Drosophila eye development

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