Honors Theses
Advisor
Yvonne Sun, Ph.D.
Department
Biology
Publication Date
4-1-2019
Document Type
Honors Thesis
Abstract
Listeria monocytogenes is a gram-positive bacillus that is commonly associated with foodborne illness. It is a facultative intracellular pathogen responsible for causing the listeriosis infection in humans which is particularly dangerous to immunocompromised individuals. L. monocytogenes pathogenesis occurs through a series of complex interactions between host and bacterial cellular machinery. The wild-type strain as well as a cardiotropic strain with high affinity for infecting cardiac tissue were used to investigate pathogenesis in L. monocytogenes. Specifically, the Listeriolysin O protein that is critical for virulence was investigated. Aerobic and anaerobic growth environments as well as short-chain fatty acid supplementation were utilized to understand how growth conditions affect the pathogenic ability of L. monocytogenes.
Permission Statement
This item is protected by copyright law (Title 17, U.S. Code) and may only be used for noncommercial, educational, and scholarly purposes
Keywords
Undergraduate research
Disciplines
Biology
eCommons Citation
Hayes, Alexander, "Pathogenic Differences in Listeria monocytogenes 10403s and Cardiotropic Strains Grown under Aerobic and Anaerobic Conditions" (2019). Honors Theses. 215.
https://ecommons.udayton.edu/uhp_theses/215
