Honors Theses
Advisor
Justin Biffinger, Ph.D.
Department
Chemistry
Publication Date
4-1-2023
Document Type
Honors Thesis
Abstract
Engineering realistic and functional tissue models presents promising possibilities in drug discovery and other biomedical research. A novel polymer with potential applications in biomedical studies was developed. I report the first synthesis and characterization (with NMR, IR, GPC, UV–vis spectroscopy, and thermal analysis) of two thermoplastic poly(alkyl piperazine succinate) diols with either propyl or hexyl alkane chains bridging the piperazines. These polyester diols were chain extended with hexamethylene diisocyanate to create highly amorphous polyester urethane thermoplastic polymers. Ru(III) and Fe(III) was then successfully coordinated with these polymers, producing a total of four different metallopolymers. The crosslinking of these complexes introduces degradative properties to the polymer, which could be valuable in biomedical studies.
Permission Statement
This item is protected by copyright law (Title 17, U.S. Code) and may only be used for noncommercial, educational, and scholarly purposes.
Keywords
Undergraduate research
eCommons Citation
Schneider, Jessica K., "Piperazine-Based Metallopolymers for Bioengineering Applications" (2023). Honors Theses. 425.
https://ecommons.udayton.edu/uhp_theses/425
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