Study of the Chemical and Physical Influences upon in Vitro Peptide-Mediated Silica Formation

Author(s)

Francisco Rodríguez, University of Dayton
Diana D. Glawe, Trinity University
Rajesh R. Naik, Air Force Research Laboratory
Kevin P. Hallinan, University of DaytonFollow
Morley O. Stone, Air Force Research Laboratory

Document Type

Article

Publication Date

2004

Publication Source

Biomacromolecules

Abstract

Herein, we report on the ability to create complex 2-D and 3-D silica networks in vitro via polycationic peptide-mediated biosilicification under experimentally altered chemical and physical influences. These structures differ from the sphere-like silica network of particles obtained in vitro under static conditions. Under chemical influences, overall morphologies were observed to shift from a characteristic network of sphere-like silica particles to a sheetlike structure in the presence of −OH groups from additives and to sharp-edged, platelike structures in the presence of larger polycationic peptide matrixes. Under physical influences, using externally applied force fields, overall silica morphologies were observed to transition from sphere-like to fiberlike and dendrite-like structures. These findings could lead to the future development of bio-inspired complex 2-D and 3-D silica micro- and nano-devices.

Inclusive pages

261–265

ISBN/ISSN

1525-7797

Comments

Permission documentation is on file.

Copyright

Copyright © 2004, American Chemical Society

Publisher

American Chemical Society

Volume

5

Issue

2

Peer Reviewed

yes

eCommons Citation

Rodríguez, Francisco; Glawe, Diana D.; Naik, Rajesh R.; Hallinan, Kevin P.; and Stone, Morley O., "Study of the Chemical and Physical Influences upon in Vitro Peptide-Mediated Silica Formation" (2004). Mechanical and Aerospace Engineering Faculty Publications. 72.
https://ecommons.udayton.edu/mee_fac_pub/72