Title

Study of the Chemical and Physical Influences upon in Vitro Peptide-Mediated Silica Formation

Document Type

Article

Publication Date

2004

Publication Source

Biomacromolecules

Abstract

Herein, we report on the ability to create complex 2-D and 3-D silica networks in vitro via polycationic peptide-mediated biosilicification under experimentally altered chemical and physical influences. These structures differ from the sphere-like silica network of particles obtained in vitro under static conditions. Under chemical influences, overall morphologies were observed to shift from a characteristic network of sphere-like silica particles to a sheetlike structure in the presence of −OH groups from additives and to sharp-edged, platelike structures in the presence of larger polycationic peptide matrixes. Under physical influences, using externally applied force fields, overall silica morphologies were observed to transition from sphere-like to fiberlike and dendrite-like structures. These findings could lead to the future development of bio-inspired complex 2-D and 3-D silica micro- and nano-devices.

Inclusive pages

261–265

ISBN/ISSN

1525-7797

Comments

Permission documentation is on file.

Publisher

American Chemical Society

Volume

5

Issue

2

Peer Reviewed

yes

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