7β-Hydroxy­artemisinin

Author(s)

Paulo B. Carvalho, University of Mississippi
Bo Liu, University of Mississippi
Yunshan Wu, University of Mississippi
John S. Williamson, University of DaytonFollow
Mitchell A. Avery, University of Mississippi

Document Type

Article

Publication Date

1-2008

Publication Source

Acta Crystallographica, Section E: Structure Reports

Abstract

Crystals of the title compound [systematic name: (3R,6R,7S,8aR,9R,12aR)-7-hydr­oxy-3,6,9-trimethyl­octa­hydro-3,12-ep­oxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one], C₁₅H₂₂O₆, were obtained from microbial transformation of artemisinin by a culture of Cunninghamella elegans. The stereochemistry of the compound is consistent with the spectroscopic findings in previously published works. A weak O—H⋯O hydrogen bond occurs in the crystal structure, together with intermolecular C—H⋯O hydrogen bonds.

Inclusive pages

o395-o396

ISBN/ISSN

2056-9890

Document Version

Published Version

Comments

This document is provided for download in compliance with the publisher's policy on self-archiving. Permission documentation is on file.

Copyright

Copyright © 2008, International Union of Crystallography

Publisher

International Union of Crystallography

Volume

E64

Issue

2

Peer Reviewed

yes

eCommons Citation

Carvalho, Paulo B.; Liu, Bo; Wu, Yunshan; Williamson, John S.; and Avery, Mitchell A., "7β-Hydroxy­artemisinin" (2008). Office for Research Publications and Presentations. 39.
https://ecommons.udayton.edu/ofr_pub/39