Title
Synthesis of Pseudopeptides Derived from (R,R)-Tartaric Acid as Potential Inhibitors of HIV-Protease
Document Type
Article
Publication Date
2006
Publication Source
Letters in Organic Chemistry
Abstract
New pseudopeptides possessing C2 symmetry and dihydroxyethylene core derived from (R,R)- tartaric acid and amino esters have been synthesized as potential inhibitors of HIV protease. The amino esters were chosen in order to interact with P1/P1 and P2/P2 subsites of the enzyme. The products were obtained in good yields without noticeable racemization.
Inclusive pages
882-886
ISBN/ISSN
1570-1786
Copyright
Copyright © 2006, Bentham Science Publishers
Publisher
Bentham Science Publishers
Volume
3
Issue
12
Peer Reviewed
yes
eCommons Citation
Barros, José C.; da Silva, Joaquim F. M.; Calazans, Alexandre R.; Tanuri, Amilcar; de Morais Brindeiro, Rodrigo; Williamson, John S.; and Antunes, Octavio A.C., "Synthesis of Pseudopeptides Derived from (R,R)-Tartaric Acid as Potential Inhibitors of HIV-Protease" (2006). Office for Research Publications and Presentations. 41.
https://ecommons.udayton.edu/ofr_pub/41
COinS
Comments
Permission documentation is on file.