Immune Signaling by HCT-8 Cells in Response to Intracellular Pathogens

Immune Signaling by HCT-8 Cells in Response to Intracellular Pathogens

Presenter(s)

Aysha Choudhury

Comments

Presentation: 9:00-10:15 a.m., Kennedy Union Ballroom

Description

Viral infections have the potential to completely overwhelm the body if appropriate measures by the immune system are not taken. Under the mentorship of Dr. Sun and Dr. Rajput, my research focused on the influence of propionate (a metabolic byproduct of gut microbiota with putative health effects) on intestinal epithelium cells infected with coronavirus (OC 43). By studying the cytopathic effects of HCT-8 cells exposed to different concentrations of propionate, we were able to gain a better understanding of how the metabolism of our gut microbiota can modulate our immune functions, something that can potentially lead to the development of new treatment options for coronaviruses, including COVID-19.

Publication Date

4-19-2023

Project Designation

Independent Research

Primary Advisor

Yvonne Sun, Mrigendra Rajput

Primary Advisor's Department

Biology

Keywords

Stander Symposium, College of Arts and Sciences

Institutional Learning Goals

Scholarship; Practical Wisdom

Immune Signaling by HCT-8 Cells in Response to Intracellular Pathogens

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